the following things are safe to delete: C:\Windows\Installer C:\Program Files\Adobe\Adobe Bridge C:\Program Files\Adobe\Adobe Help Center C:\Program Files\Adobe\Adobe Stock Photos C:\Program Files\Adobe\Adobe Utilities C:\Program Files\Adobe\Adobe Photoshop CS2\Samples C:\Program Files\Adobe\Adobe Photoshop CS2\ImageReady.exe C:\Program Files\Adobe\Adobe Photoshop CS2\Scripting Guide C:\Program Files\Adobe\Adobe Photoshop CS2\Helpers C:\Program Files\Adobe\Adobe Photoshop CS2\Help C:\Program Files\Adobe\Adobe Photoshop CS2\Required\ImageReady Default Actions C:\Program Files\Adobe\Adobe Photoshop CS2\Plug-Ins\Adobe ImageReady Only C:\Program Files\Common Files\Adobe\Linguistics C:\Program Files\Common Files\Adobe\Color\Settings\ExtraSettings C:\Program Files\Common Files\Adobe\PDFL\6.0 C:\Program Files\Common Files\Adobe\PDFL\7.0 C:\Program Files\Common Files\Adobe\Spelling C:\Program Files\Adobe\Adobe Photoshop CS2\AdobeUpdater.dll anything in C:\Program Files\Common Files\Adobe\Color\Profiles\Recommended that you think you don't need note: do NOT delete the Activation directory -- the files in there don't do anything, but Photoshop will not start if it's not present. note: if you delete c:\windows\installer, you'll need the original .msi file to uninstall Photoshop (and anything else that uses .msi files). note: after deleting, you may get "could not complete your request because of a program error" on photoshop startup. This is normal -- photoshop is trying to run automatic updates. total space saved: 357MB